John and Mark explore the science of weight loss and metabolism. They will review some critical “environmental inputs” that are known to disrupt fat-burning and create insulin and leptin resistance. Insulin and leptin resistance are the cornerstones of obesity, insulin resistance, diabetes and is a major metabolic risk for many chronic complex diseases. Insulin drives fat storage. It is impossible to burn fat as a fuel in a sustained fashion when insulin levels are high. Leptin resistance in our brains interferes with satiety. We interpret…”keep eating” and “lay-low” so as to avoid burning precious energy.  These are the exact opposite signaling interpretations one wants to lose weight and sustain the loss.

John and Mark will provide some news to use for actionable lifestyle changes that can better calibrate these systems.