Supplements and Depression

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In this episode of The Health Edge Mark and John review a recent paper on the efficacy of supplementation in the management of depression. The efficacy and safety of nutrient supplements in the treatment of mental disorders: a meta-review of meta-analyses of randomized controlled trials. (World Psychiatry 2019;18:308–324)

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Check out the lates episode of The health Edge

Air Pollution and Health Outcomes

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In this videocast of The Health Edge Mark and John discuss two recently published papers:

1. Ambient Particulate Air Pollution and Daily Mortality in 652 Cities New England Journal of Medicine August 2019
2. Environment dominates over host genetics in shaping human gut microbiota. Nature 2018
Ambient Particulate Air Pollution and Daily Mortality in 652 CitiesDownload
Environment dominates over host genetics in shaping human gut microbiotaDownload

Plant vs Animal-Based Protein Sources

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In this videocast of The Health Edge Mark and John share a few reflections on the controversial debate between the risks/benefits of plant versus animal based protein sources.
TMAO: The Gut-Heart Connection
Associations of egg consumption with cardiovascular disease in a cohort study of 0.5 million Chinese adultsDownload
A Systematic Review of Renal Health in Healthy Individuals Associated with Protein Intake above the US Recommended Daily Allowance in Randomized Controlled Trials and Observational StudiesDownload
Association of IGF-I Levels with Muscle Strength and Mobility in Older WomenDownload
Insulin-like growth factor 1 (IGF1), IGF binding protein 3 (IGFBP3), and breast cancer risk- pooled individual data analysis of 17 prospective studiesDownload

Vitamin K2 and Cardiovascular Risk

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In this episode of The Health Edge Mark and John review a recent research study from the American Heart Association that links low vitamin K2 levels with significant cardiovascular risk. Mark and John suggest some strategies for improving K2 levels and for improving vascular “elasticity”.

Coronary-CA-BMJ-2013Download
Central Hemodynamics in Relation to Circulating Desphospho-Uncarboxylated Matrix Gla Protein- A Population StudyDownload
Updates to the Ultimate Vitamin K2 Resource
From Chris Masterjohn PhD