Cardiometabolic Health: Are you a member of this exclusive club?
In this episode of The Health Edge Mark and John review a recent study published by the Journal of the American College of Cardiology, Trends and Disparities in Cardiometabolic Health Among U.S. Adults, 1999-2018. Mark and John reflect on how we got here and why this is so important to recognize and respond to. Lifestyle drivers and interventions are discussed that have the potential to powerfully reverse these concerning trends. Article referenced: https://pubmed.ncbi.nlm.nih.gov/35798…
You Tube recording can be found at: https://www.youtube.com/watch?v=_lBUR_llqfA&t=9s&ab_channel=TheHealthEdge
Fructose, Uric acid and Cardiometabolic Risk
Is it possible that consuming too much fruit could be detrimental to your health? Are all fruits the same? In this recording of The Health Edge Mark and John will explore the relationship between dietary fructose intake (from sugar and high fructose corn syrup and fruits), endogenous metabolic conversion of glucose to fructose (high glycemic foods), and high salt intake (> 5,000 mg sodium/day) with high uric acid cardiometabolic syndrome risk. The evolutionary biologic importance of these pathways as an ancient survival mechanism when food sources were limited has become a major driver of chronic, complex disease in a contemporary context of high sugar and abundant year-round fruit availability. They elaborate on the research of Robert Lustig MD (UCSF), Richard Johnson MD (University of Colorado)and Robert Ludwig MD, PhD (Harvard). Enjoy!
The-effects-of-apples-and-apple-juice-on-acute-plasma-uric-acid-concentration-a-randomized-controlled-trialDownload
The-Effect-of-6-months-Fruit-rich-Diet-on-Liver-Steatosis-Liver-Enzymes-Insulin-Resistance-and-Lipid-Profile-in-Patients-With-Non-alcoholic-Fatty-Liver-Disease-a-Randomized-Clinical-TrialDownload
Can Vitamin D supplementation slow biologic age?
In this episode of The Health Edge Mark and John review two papers that suggest higher levels of vitamin D via supplementation may slow our biologic clocks as measured by epigenetic methylation patterns. The implications are fascinating! YouTube link: https://youtu.be/O3UD62Pk9fE Papers reviewed: Vitamin D supplementation is associated with slower epigenetic aging https://pubmed.ncbi.nlm.nih.gov/35562… Effects of Vitamin D3 Supplementation on Epigenetic Aging in Overweight and Obese African Americans With Suboptimal Vitamin D Status: A Randomized Clinical Trial https://pubmed.ncbi.nlm.nih.gov/30256…
Can Healthy Lifestyle Regress Biologic Age?
In this episode of The Health Edge Mark and John review a recently published paper affirming proof of concept: healthy lifestyle may in fact reverse biologic aging or slow “biologic clocks” via epigenetic methylation patterns.
Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064200/
You Tube video can be seen here:
https://www.youtube.com/watch?v=MQahbN4pzxI&t=2s&ab_channel=TheHealthEdge
An Overview of The Science of Aging and Longevity 2022
In this episode of The Health Edge, Mark shares a recording from January 21, 2022 reviewing the current science of aging and longevity. This was the first of a series of 6 webinars sponsored by OLLI Berkshires. https://berkshireolli.org/ScienceOfAgingWinter22
NAFLD: Non-Alcohol Fatty Liver Disease Reversal
In this episode of The Health Edge Mark and John review a paper demonstrating significant reductions in NAFLD with both 5:2 fasting mimicking or LCHF over just 12 weeks. Article can be found at: https://www.jhep-reports.eu/article/S2589-5559(21)00032-X/fulltext
Chronology of Insulin Resistance, Obesity and Inflammation
In this episode of The Health Edge mark and John review an important paper that suggests obesity to be more a consequence of higher insulin than a cause. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2749271
Glycemic Index, Glycemic Load, and Cardiovascular Disease and Mortality
In this Health Edge videocast, John and Mark review a recent paper published in the New England Journal of Medicine that links higher intake of high-glycemic foods and beverages with higher all-cause mortality and cardiovascular disease. https://www.nejm.org/doi/full/10.1056/NEJMoa2007123
