In this episode of The Health Edge Mark and John review some papers that challenge the well accepted clinical meme that lowering LDL should be the focal point of reducing CV risk and all-cause mortality risk. Papers referenced: https://www.nature.com/articles/s4159… https://bmjopen.bmj.com/content/6/6/e… https://www.ncbi.nlm.nih.gov/pmc/arti…
Sodium Restriction and Insulin Resistance
In this episode of The Health Edge Mark and John review a recent paper drawing connections between excessive sodium restriction and insulin resistance. This adds to a growing body of research suggesting the restriction of sodium below 3-4 gms/day may in fact add to cardiometabolic risk. Current guidelines of 2300 mg/day or less fall well below these levels.
Erythritol and Cardiovascular Risk: Is there a real concern here?
In this Health Edge podcast recording, Mark and John review a recent paper that drew a strong relationship between erythritol levels in the blood with major adverse cardiovascular (MACE) events. Mark and John anayize the study and offer perspective. https://www.nature.com/articles/s4159… Another recent review of risks and benefits of erythritol. https://www.ncbi.nlm.nih.gov/pmc/arti…
Alzheimer’s and Mild Cognitive Impairment: Is this epidemic a one-way street?
Few age-related diseases are more devastating than Alzheimer’s. A recent study from Columbia University suggests in individuals 65+ years of age, 10% have a dementia diagnosis and almost 25% have a diagnosis of MCI or mild cognitive decline. For the 90+ age demographic, over 30% have a dementia diagnosis. The costs to the individuals and those who care for them is staggering. In this recording, mark and John review the data from this paper (Annals of Neurology October 2022) and offer a different perspective on how to prevent, what today, feels like a one-way street.
Saturated Fat Intake and Diabetes-Cardiometabolic Risk
In this episode of The Health Edge Mark and John review some recent studies that continue to challenge the long held belief that saturated fatty acid intake (SFAs) is directly linked to diabetes and cardiometabolic risk.
https://www.thelancet.com/article/S0140-6736(17)32252-3/fulltext
https://pubmed.ncbi.nlm.nih.gov/36056919/